Our Services

PCC Tasler - Preclinical Consulting

Our Services shall enable SMEs (academic or biotech settings) to acquire creative and pragmatic solutions, a second opinion, an outside view on the internal strategy, and/or recommendations from an industry perspective – and this quickly and at an affordable rate to comply with a usually tight budget.

Based on 20+ years hands-on experience within the biotech landscape and collaborative business, our goal is to develop tailor-made strategies, solutions and/or evaluations for numerous questions, problems and/or future advancements for drug discovery projects, mainly involving small molecules, for the customer.  

Services encompass, but are not limited to, evaluating and/or designing project stages from identified Lead molecule up to pre-IND preclinical status:

  • Lead optimization strategies

  • Project status evaluations including GAP analyses for identification of potential nexts steps to advance the program to a next level

  • Suggestions of profiling packages with regard to physicochemical properties

  • Assay selection (biochemical and cellular)

  • ADMET profiling cascades

  • In vivo strategy, comprising PK studies, formulation development, and selection of appropriate therapeutic animal models

  • General top level strategies for future development, including the development of a potential Target Product Profile  

  • If required, respective CROs for performing different work packages can be suggested as well

Such outline of work packages is not intended to potentially leave the customer with a vast quantity of new data points, interpretation and discussion of such results within the given context can also be selected as part of the Services, leading to scrutiny of existing ideas and strategies and time- and cost-efficient adjustment and/or advancement of such ideas and strategies based on the new data acquired.

If own projects shall be prepared for out-licensing, or if competitor projects are available for in-licensing, respective project evaluations are offered as well:

  • as a SWOT analysis (strength, weakness, opportunities, threats) for own projects based on the intended scope of the Due Diligence package

  • as a Third Party Due Diligence for external projects, which allows the generation of a project appraisal without contaminating the own knowledge base, thus avoiding potential confidentiality and/or exclusivity clashes

For inquiries and requests, please contact us: [email protected]

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PCC Tasler - Preclinical Consulting

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